Health / Medical Topics

    Shiga Toxin

    Definition 1

    A bacterial toxin produced by Shigella dysenteriae and by some strains of E. coli that inhibits protein synthesis by blocking the interaction of ribosomal RNA with peptide elongation factors. The non-catalytic beta subunit of Shiga toxin may be useful as a fusion vector for induction of antigen-specific cytotoxic T lymphocyte responses. (NCI Thesaurus)

    Definition 2

    A toxin produced by SHIGELLA DYSENTERIAE. It is the protype of class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. (NLM, Medical Subject Headings)




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