| Health / Medical Topics |
Sickle Cell Dactylitis
A severe acute inflammatory response affecting the hands and feet of individuals with with sickle cell disease, sickle cell-hemoglobin C disease or sickle cell-beta-thalassemia. It is caused by vaso-occlusive episodes leading to ischemia and finally infarction of the distal portions of the extremities. Clinical signs of pain, swelling and tenderness of digits usually begin in early childhood and may be the initial manifestations of sickle cell anemia. Clinical course is self-limited with instances typically lasting a few weeks and occuring during sickling crises. An initial episode before the age of 1 strongly correlates with a more severe disease course. (NCI Thesaurus)
YOU MAY ALSO LIKE
The determination of the number of sickle cells present in a sample.
An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last…
A heterozygous state in which a person has a hemoglobin S allele along with a beta-thalassemia allele. The severity of the condition…
A mild form of sickle cell thalassemia characterized by the presence of hemoglobin S and a small amount of hemoglobin A in…
A form of sickle cell thalassemia characterized by the absence of hemoglobin A. Patients usually have severe anemia identical to that seen…
A sensation of discomfort or distress that makes the individual queasy or nauseated.
