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Siplizumab
Pronunciation
Definition 1
A monoclonal antibody that is being studied in the treatment of certain lymphoproliferative disorders and psoriasis. Also called MEDI-507. (NCI Dictionary)
Definition 2
A humanized monoclonal immunoglobulin G1 antibody with potential antineoplastic activity. Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby triggering a host immune response that results in lysis of CD2+ cells, selective suppression of the immune system, and control of activated T cell growth. (NCI Thesaurus)
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