Health / Medical Topics

    SKP2 wt Allele

    Human SKP2 wild-type allele is located within 5p13 and is approximately 32 kb in length. This allele, which encodes S-phase kinase-associated protein 2, is involved in cell cycle arrest at the G1/S transition of the cell cycle. SKP2 variant alleles have been established as alleles that are causally involved in the pathogenesis of lymphomas. (NCI Thesaurus)




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