| Health / Medical Topics |
SLPI wt Allele
Human SLPI wild-type allele is located within 20q12 and is approximately 2 kb in length. This allele, which encodes antileukoproteinase 1 protein, plays a role in the protection of epithelial tissues from degradation by serine proteases. The SLPI gene is overexpressed in certain types of cancer such as non-small cell lung carcinomas and ovarian carcinomas. (NCI Thesaurus)
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