SMAD6 wt Allele

Human SMAD6 wild-type allele is located within 15q21-q22 and is approximately 80 kb in length. This allele, which encodes mothers against decapentaplegic homolog 6 protein, plays a role in the regulation of both heart and blood vessel development and maintenance. (NCI Thesaurus)

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SMAD6 Protein

Encoded by MADH6 Gene (SMAD Family), ubiquitous (predominantly vascular endothelium) SMAD6 Protein Isoforms A (496-aa 53.5-kD) and B (235-aa) act similar to…

SMAD6 Gene

This gene is involved in signal transduction and regulation of transcription. It also plays a role in development.

SMAD4 wt Allele

Human SMAD4 wild-type allele is located in the vicinity of 18q21.1 and is approximately 50 kb in length. This allele, which encodes…

SMAD4 Gene

This gene plays a role in signal transduction and transcriptional activation. It is also involved in suppression of angiogenesis.

SMAD3 wt Allele

Human SMAD3 wild-type allele is located in the vicinity of 15q22.33 and is approximately 130 kb in length. This allele, which encodes…

SMAD3 Gene

This gene is involved in signal transduction and apoptosis. It also plays a role in the regulation of both steroid synthesis and…