| Health / Medical Topics |
Small Inducible Cytokine B6
Encoded by human CXCL6 Gene (Intercrine Alpha/Chemokine CXC Family), secreted 114-aa 12-kD (precursor) Small Inducible Cytokine B6 is a potent inflammatory mediator and chemotactic factor for neutrophilic granulocytes that regulates leukocyte trafficking through interactions with a subset of 7-transmembrane, G protein-coupled receptors CXCR1 and CXCR2 and activates gelatinase B (MMP9) release from granulocytes. Human and bovine GCP2 are 67% identical at the amino acid level. (NCI Thesaurus)
YOU MAY ALSO LIKE
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas by human CXCL14 Gene (Intercrine Alpha/Chemokine CXC Family), secreted immunoregulatory…
Expressed in liver, spleen, lymph node, Peyer's patches, appendix, stomach, salivary gland, mammary gland, and fetal spleen by human CXCL13 Gene (Intercrine…
Encoded by INF gamma- and INF beta-induced human CXCL11 Gene (Intercrine Alpha/Chemokine CXC Family) in leukocytes, pancreas, liver, astrocytes, thymus, spleen, lung,…
A member of the alpha-chemokine family, IP10 is secreted from macrophages, endothelial cells, and keratinocytes in response to IFN-gamma and activates a…
Chemokines, a family of small cytokines, attract leukocytes and possess various immunomodulating functions. CC chemokines influence mononuclear cell types. Human…
Small Inducible Cytokine A7, encoded by the CCL7 gene, is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is…
