sn-1,2-Didecanoylglycerol

A synthetic lipid second messenger. As an analog of the second messenger diacylglycerol, sn-1,2-didecanoylglycerol substitutes for diacylglycerol in the cascade of calcium and phospholipid dependent PKC activation. Topical application of this agent results in a striking inflammatory response characterized by edema, extensive epidermal infiltration of neutrophils and macrophages, intraepidermal microabscesses. sn-1,2-Didecanoylglycerol is used as a tumor promoter in experimental animal models of skin cancer due to its stimulation of epidermal protein kinase C activity. (NCI Thesaurus)

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SN Term Type

The NCI term type designation for a chemical structure name.

SMYD3 wt Allele

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SMYD3 Gene

This gene plays a regulatory role in histone methyltransferase activity and transcription.

Smudge Cell Count

The determination of the number of smudge cells present in a sample.

SMPD4 wt Allele

Human SMPD4 wild-type allele is located in the vicinity of 2q21.1 and is approximately 31 kb in length. This allele, which encodes…

SMPD4 Gene

This gene is involved in ceramide biosynthesis.