SOD2 wt Allele

Human SOD2 wild-type allele is located in the vicinity of 6q25.3 and is approximately 14 kb in length. This allele, which encodes superoxide dismutase [Mn], mitochondrial protein, is involved in the conversion of superoxide radicals to molecular oxygen and hydrogen peroxide. It also plays a role in modifying iron toxivity. Certain allelic variants of the SOD2 gene are associated with nonfamilial idiopathic cardiomyopathy. (NCI Thesaurus)

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SOD2 Gene

This gene is involved in the detoxification of superoxide radicals produced within mitochondria.

SOD1 wt Allele

Human SOD1 wild-type allele is located within 21q22 and is approximately 9 kb in length. This allele, which encodes superoxide dismutase [Cu-Zn]…

SOD1 inhibitor ATN-224

A substance being studied in the treatment of cancer. It may prevent the growth of new blood vessels that tumors need to…

SOD1 Gene

This gene plays a role in the detoxification of superoxide radicals in the cytosol.

SOCS3 wt Allele

Human SOCS3 wild-type allele is located in the vicinity of 17q25.3 and is approximately 3 kb in length. This allele, which encodes…

SOCS3 Gene

This gene is involved in the regulation of cytokine-mediated signaling.