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SOLUBILITY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The quality of being soluble and easily dissolved in liquid
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("solubility" is a kind of...):
quality (an essential and distinguishing attribute of something or someone)
Antonym:
insolubility (the quality of being insoluble and difficult to dissolve in liquid)
Derivation:
soluble ((of a substance) capable of being dissolved in some solvent (usually water))
Sense 2
Meaning:
The property (of a problem or difficulty) that makes it possible to solve
Synonyms:
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("solubility" is a kind of...):
property (a basic or essential attribute shared by all members of a class)
Antonym:
insolubility (the property (of a problem or difficulty) that makes it impossible to solve)
Derivation:
soluble (susceptible of solution or of being solved or explained)
Sense 3
Meaning:
The quantity of a particular substance that can dissolve in a particular solvent (yielding a saturated solution)
Classified under:
Nouns denoting quantities and units of measure
Hypernyms ("solubility" is a kind of...):
definite quantity (a specific measure of amount)
Domain category:
solution (a homogeneous mixture of two or more substances; frequently (but not necessarily) a liquid solution)
Derivation:
soluble ((of a substance) capable of being dissolved in some solvent (usually water))
Context examples:
The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.
(Paclitaxel-loaded polymeric micelle, NCI Thesaurus)
This leads to the introduction of a polar functional group to the compound, enhances their water solubility and renal excretion.
(Phase I Enzymes Inhibitor, NCI Thesaurus)
The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.
(Paclitaxel poliglumex, NCI Thesaurus)
Compared to an unconjugated fumagillin analog, XMT-1107 exhibits improved solubility and an extended half life due to its PHF backbone.
(Fumagillin-Derived Polymer Conjugate XMT-1107, NCI Thesaurus)
Vitamins may be classified according to their solubility either in lipids (vitamins A, D, E, K, F) or in water (vitamins C, B-complex).
(Multivitamin, NCI Thesaurus)
Due to the hydrophilic nature of polyethylene glycol, this formulation increases the water-solubility of cisplatin and decreases the nephrotoxicity and neurotoxicity associated with the administration of cisplatin alone.
(Micellar Nanoparticle-Encapsulated Cisplatin NC-6004, NCI Thesaurus)
Gallium nitrate localizes preferentially to areas of bone resorption and remodeling and inhibits osteoclast-mediated resorption by enhancing hydroxyapatite crystallization and reduction of bone mineral solubility.
(Gallium nitrate, NCI Thesaurus)
Beta-cyclodextrin is employed for numerous applications to enhance solubility and availability of various water-soluble and water-insoluble pharmacological agents.
(Beta-methyl Cyclodextrin, NCI Thesaurus)
Compared to carboplatin alone, dicycloplatin shows enhanced solubility and stability in aqueous solution and appears to have a more favorable toxicity profile.
(Dicycloplatin, NCI Thesaurus)
Separation of a product from a saturated solution by cooling the liquid or adding precipitants which lower the solubility of the desired product so that it forms crystals.
(Crystallization Purification, NCI Thesaurus)
