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Sonidegib
Pronunciation
A drug used to treat locally advanced basal cell carcinoma (BCC) that has come back after surgery or radiation therapy. It is also used in patients who cannot be treated with surgery or radiation therapy. Sonidegib is also being studied in the treatment of other types of cancer. Sonidegib blocks a type of protein involved in tissue growth and repair and may block the growth of cancer cells. It is a type of hedgehog signaling pathway antagonist. Also called erismodegib, LDE225, and Odomzo. (NCI Dictionary)
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The result of the sonic hedgehog/patch pathway signaling status is not known or the test has not been performed.
A genetic finding indicating that the sonic hedgehog/patch pathway is inactivated.
A genetic finding indicating that the sonic hedgehog/patch pathway is activated.
Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) and Desert Hedgehog (Dhh), that play…
Expressed only during embryogenesis by human SHH Gene (Hedgehog Family), 462-aa 50-kDa (precursor) Sonic Hedgehog Homolog is the notochord inductive signal in…
