| Health / Medical Topics |
Sorafenib
Definition 1
A synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. (NCI Thesaurus)
Definition 2
A drug used to treat advanced kidney cancer and a type of liver cancer that cannot be removed by surgery. It is also being studied in the treatment of other types of cancer. Sorafenib stops cells from dividing and may prevent the growth of new blood vessels that tumors need to grow. It is a type of kinase inhibitor and a type of antiangiogenesis agent. (NCI Dictionary)
YOU MAY ALSO LIKE
Written instructions for doing a specific task in a certain way. In clinical trials, SOPs are set up to store records, collect…
Black particulate matter formed as by-products of combustion or pyrolysis of organic (carbon-containing) materials, such as coal, wood, fuel oil, waste oil,…
A state in north western Mexico on the Gulf of California. Its capital is Hermosillo.
A computer picture of areas inside the body created by high-energy sound waves. The sound waves are bounced off internal tissues or…
A drug used to treat locally advanced basal cell carcinoma (BCC) that has come back after surgery or radiation therapy. It is…
A technique that uses sound energy to agitate or disrupt the components of a sample.
