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SPASTIC
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A person suffering from spastic paralysis
Classified under:
Hypernyms ("spastic" is a kind of...):
paralytic (a person suffering from paralysis)
II. (adjective)
Sense 1
Meaning:
Affected by involuntary jerky muscular contractions; resembling a spasm
Example:
spastic movements
Synonyms:
convulsive; spasmodic; spastic
Classified under:
Similar:
unsteady (subject to change or variation)
Derivation:
spasticity (the quality of moving or acting in spasms)
Sense 2
Meaning:
Suffering from spastic paralysis
Example:
a spastic child
Classified under:
Similar:
ill; sick (affected by an impairment of normal physical or mental function)
Derivation:
spastic paralysis (a loss or deficiency of motor control with involuntary spasms caused by permanent brain damage present at birth)
spasticity (the quality of moving or acting in spasms)
Sense 3
Meaning:
Relating to or characterized by spasm
Example:
spastic paralysis is a spastic form of cerebral palsy
Classified under:
Relational adjectives (pertainyms)
Pertainym:
spasm (a painful and involuntary muscular contraction)
Derivation:
spastic paralysis (a loss or deficiency of motor control with involuntary spasms caused by permanent brain damage present at birth)
spasticity (the quality of moving or acting in spasms)
Context examples:
It is characterized by spastic quadriplegia, pseudobulbar palsy and encephalopathy.
(Central Pontine Myelinolysis, NCI Thesaurus)
Chromosomal rearrangements affecting the gene may be associated with epileptic encephalopathy with spastic tetraparesis and severe psychomotor retardation associated with cerebral atrophy, developmental delay with recurrent infections or lymphoma.
(NKAIN2 wt Allele, NCI Thesaurus)
A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements of athetoid cerebral palsy.
(Mixed Cerebral Palsy, NCI Thesaurus)
An X-linked inherited disorder caused by mutations in the PLP1 gene on chromosome X. The signs and symptoms are the result of defective myelination of the central nervous system and include nystagmus, hypotonia, tremor, ataxia, spastic quadriparesis, and diffuse leukoencephalopathy.
(Pelizaeus-Merzbacher Disease, NCI Thesaurus)
Mutation of the gene is associated with hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS), mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA or CRASH syndrome), spastic paraplegia 1, X-linked and agenesis of the corpus callosum, X-linked, partial and may contribute to intestinal aganglionosis in Hirschsprung disease.
(L1CAM wt Allele, NCI Thesaurus)
