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Splice-Site Mutation
Any mutation that occurs within the discrete sequences comprising the 5' or 3' splice sites of a gene that has a spliced message. Splice-site mutation may result in a deletion or insertion of extraneous amino acids in the gene product or a change in the reading frame of the spliced message. (NCI Thesaurus)
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An inherited single base substitution in a sequence of eukaryotic DNA located in either an acceptor (3' or downstream) or donor (5'…
Abnormal enlargement of the spleen.
A vague term that usually refers to the phagocytic cells (macrophages) of the spleen.
The part of the spleen that consists of nodules and other lymphatic concentrations.
A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein.
The veins within the spleen that drain blood from the sinuses of the pulp and unite at the hilum to form the…
