Splicing Factor Proline-and Glutamine-Rich

Splicing factor, proline- and glutamine-rich protein (707 aa, ~76 kDa) is encoded by the human SFPQ gene. This protein may be involved in messenger RNA processing, transcriptional regulation and the modulation of DNA secondary structure. (NCI Thesaurus)

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Splicer Device Component

A device designed to join pieces of a material into a continuous length.

Spliceosome Pathway

After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined…

Spliceosome Assembly Pathway

The assembly of the spliceosome is a dynamic process that involves both small ribonucleoprotein particles (snRNPs), and non-snRNP proteins. The complete…

Splice-Site Mutation Abnormality

An aberrant DNA sequence that results from a mutation in a sequence of eukaryotic DNA located in either an acceptor (3' or…

Splice-Site Mutation

Any mutation that occurs within the discrete sequences comprising the 5' or 3' splice sites of a gene that has a spliced…