SPN wt Allele

Human SPN wild-type allele is located in the vicinity of 16p11.2 and is approximately 8 kb in length. This allele, which encodes leukosialin protein, plays a role in both chemotaxis and leukocyte migration. (NCI Thesaurus)

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SPN Gene

This gene is involved in leukocyte migration.

Splitting Pain

An intense sensation of discomfort or distress that feels like being cut apart.

Split-Hand/Foot Malformation Type 5

Split-hand/foot malformation mapped to chromosome 2q31.

Split-Hand/Foot Malformation Type 3

Split-hand/foot malformation mapped to chromosome 10q24.

Split-Hand/Foot Malformation Type 1

Split-hand/foot malformation mapped to chromosome 7q21.3

Split-Hand/Foot Malformation

A rare genetic disorder often inherited in an autosomal manner characterized by limb malformations including syndactyly, median clefts of the hands and/or…