Health / Medical Topics |
Squamous Hyperplasia of the Mouse Skin with Atypia
An increase in the number of keratinocytes composing the epidermis with significant cytologic atypia of keratinocytes. Criteria for atypia include increase in cell size (>1.5 fold nuclear enlargement relation to basal keratinocytes), hyperchromasia, and crowding of basal keratinocytes. (NCI Thesaurus/MMHCC)
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A simple or stratified flat epithelium.
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Composed of airway epithelial cells with squamous metaplasia. Degree of atypia, maturation, orientation towards the basal membrane and involvement of full thicknessā¦
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