SRD5A3 wt Allele

Human SRD5A3 wild-type allele is located 4q12 and is approximately 27 kb in length. This allele, which encodes probable polyprenol reductase protein, is involved in both the metabolism of testosterone and the early steps of protein N-linked glycosylation. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. (NCI Thesaurus)

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SRD5A3 Gene

This gene plays a role in the metabolism of testosterone.

SRD5A2 wt Allele

Human SRD5A2 wild-type allele is located within 2p23 and is approximately 56 kb in length. This allele, which encodes 3-oxo-5-alpha-steroid 4-dehydrogenase 2…

SRD5A2 Gene

This gene is involved in androgen metabolism and sexual differentiation.

SRD5A1 wt Allele

Human SRD5A1 wild-type allele is located 5p15 and is approximately 36 kb in length. This allele, which encodes 3-oxo-5-alpha-steroid 4-dehydrogenase 1 protein,…

SRD5A1 Gene

This gene is involved in the metabolism of androgens.

Src/Abl Kinase Inhibitor AZD0424

An orally bioavailable small molecule tyrosine kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Upon oral administration,…