SRGAP3/RAF1 Fusion Gene

A fusion gene (~3.5 kb) that results from a tandem duplication at chromosome 3p25 which fuses exon 12 of the SRGAP3 gene to exon 10 of the RAF1 gene. This fusion is associated with pilocytic astrocytoma. (NCI Thesaurus)

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SRGAP3 wt Allele

Human SRGAP3 wild-type allele is located in the vicinity of 3p25.3 and is approximately 382 kb in length. This allele, which encodes…

SRGAP3 Gene

This gene plays a role in GTPase-mediated signaling.

SRF wt Allele

Human SRF wild-type allele is located in the vicinity of 6p21.1 and is approximately 10 kb in length. This allele, which encodes…

SRF Gene

This gene is involved in the regulation of transcription, cell proliferation and differentiation.

SRF Activation Pathway

Serum response factor (SRF) is a transcription factor, which binds to a serum response element (SRE) associated with a variety of genes…

SREBF1 wt Allele

Human SREBF1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 26 kb in length. This allele, which encodes…