Health / Medical Topics |
ST14 wt Allele
Human ST14 wild-type allele is located within 11q24-q25 and is approximately 51 kb in length. This allele, which encodes suppressor of tumorigenicity 14 protein, is involved in the cleavage/activation of other proteases and latent growth factors. Decreased expression of the ST14 gene is associated with tumor metastasis. (NCI Thesaurus)
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