Library / English Dictionary

    STABILIZATION

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The act of stabilizing something or making it more stableplay

    Example:

    stabilization means that the product can be handled under atmospheric conditions

    Synonyms:

    stabilisation; stabilization

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("stabilization" is a kind of...):

    normalisation; normalization; standardisation; standardization (the imposition of standards or regulations)

    Hyponyms (each of the following is a kind of "stabilization"):

    equilibration (stabilization by bringing into equilibrium)

    Antonym:

    destabilization (the action of destabilizing; making something less stable (especially of a government or country or economy))

    Derivation:

    stabilize (make stable and keep from fluctuating or put into an equilibrium)

    Sense 2

    Meaning:

    The act of making something (as a vessel or aircraft) less likely to overturnplay

    Synonyms:

    stabilisation; stabilization

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("stabilization" is a kind of...):

    improvement (the act of improving something)

    Domain category:

    aircraft (a vehicle that can fly)

    Derivation:

    stabilize (support or hold steady and make steadfast, with or as if with a brace)

    Credits

     Context examples: 

    DNA-binding HMG proteins appear to have roles in matrix stabilization, ssDNA protection, replication, and transcription that influence cell growth, proliferation, differentiation, and death.

    (HMG Family Gene, NCI Thesaurus)

    In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes.

    (Patupilone, NCI Thesaurus)

    Edotecarin inhibits the enzyme topoisomerase I through stabilization of the DNA-enzyme complex and enhanced single-strand DNA cleavage, resulting in inhibition of DNA replication and decreased tumor cell proliferation.

    (Edotecarin, NCI Thesaurus)

    This protein plays a role in the stabilization of cyclin-dependent kinase inhibitor 1 protein.

    (FK506-Binding Protein-Like, NCI Thesaurus)

    Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.

    (Ixabepilone, NCI Thesaurus)

    Stabilization of microtubule polymerization causes interruption of mitosis and is the mode of action of several antineoplastic agents.

    (Microtubule Polymerization Process, NCI Thesaurus)

    This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in the allergic process.

    (Pemirolast, NCI Thesaurus)

    This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process.

    (Pemirolast Potassium, NCI Thesaurus)

    Stabilization with tris instead of lysine further increases stability and may further decrease nephrotoxicity.

    (Palifosfamide Tromethamine, NCI Thesaurus)

    This stabilization is dependent on the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC.

    (p21 H-Ras Protein, NCI Thesaurus)


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