| Health / Medical Topics |
STAT4 wt Allele
Human STAT4 wild-type allele is located within 2q32.2-q32.3 and is approximately 122 kb in length. This allele, which encodes signal transducer and activator of transcription 4 protein, is involved in both the transcriptional activation of interleukin-12 responsive genes and T helper cell differentiation. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in signal transduction and activation of transcription. It plays a role in regulation of T-helper cell differentiation. …
Human STAT3 wild-type allele is located in the vicinity of 17q21 and is approximately 75 kb in length. This allele, which encodes…
STATs, Signal Transducers and Activators of Transcription, are transcription factors that are phosphorylated by JAK kinases in response to cytokine activation to…
An orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3), with potential antineoplastic activity. STAT3 inhibitor OPB-51602 inhibits the…
An orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3), with potential antineoplastic activity. OPB-31121 inhibits the phosphorylation of…
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell…
