Subcutaneous Panniculitis-Like T-Cell Lymphoma

A cytotoxic primary cutaneous T-cell lymphoma. Recent studies suggest there are at least two groups of subcutaneous panniculitis-like T-cell lymphomas, each with distinct histologic features, immunophenotypic profile, and prognosis. One group has an alpha/beta, CD8 positive phenotype, involves only subcutaneous tissues, and usually has an indolent clinical course. The second group has a gamma/delta phenotype, is CD8 negative, often co-expresses CD56, is not confined to the subcutaneous tissues, and usually has a poor prognosis. In the recent WHO-EORTC classification, the term subcutaneous panniculitis-like T-cell lymphoma is reserved for cases with an alpha/beta, CD8 positive phenotype. Cases with a gamma/delta phenotype are included in the group of cutaneous gamma/delta T-cell lymphomas. (NCI Thesaurus)

YOU MAY ALSO LIKE

Subcutaneous Nodule

A small palpable mass in the subcutaneous tissues.

Subcutaneous Nodular Fasciitis

A rapid-growing, non-encapsulated benign neoplasm arising from the subcutaneous tissues. It is characterized by the growth of non-hyperchromatic spindle-shaped fibroblasts in a…

Subcutaneous Mastectomy

A surgical procedure that removes the breast tissue while leaving the skin, nipple, areola, and chest wall muscles intact.

Subcutaneous

Beneath the skin.

Subculturing

Transferring cultured cells, with or without dilution, from one culture vessel to another.

Subcostal Vein

Either of two veins (right or left) under the twelfth rib.