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    SUPPRESSION

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    (psychology) the conscious exclusion of unacceptable thoughts or desiresplay

    Synonyms:

    inhibition; suppression

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("suppression" is a kind of...):

    abstinence (act or practice of refraining from indulging an appetite)

    Domain category:

    psychological science; psychology (the science of mental life)

    Derivation:

    suppress (put out of one's consciousness)

    Sense 2

    Meaning:

    Forceful prevention; putting down by power or authorityplay

    Example:

    the stifling of all dissent

    Synonyms:

    crushing; quelling; stifling; suppression

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("suppression" is a kind of...):

    bar; prevention (the act of preventing)

    Hyponyms (each of the following is a kind of "suppression"):

    crackdown (severely repressive actions)

    Derivation:

    suppress (bring under control by force or authority)

    suppress (come down on or keep down by unjust use of one's authority)

    Sense 3

    Meaning:

    The act of withholding or withdrawing some book or writing from publication or circulationplay

    Example:

    a suppression of the newspaper

    Synonyms:

    curtailment; suppression

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("suppression" is a kind of...):

    restraint (the act of controlling by restraining someone or something)

    Derivation:

    suppress (bring under control by force or authority)

    Sense 4

    Meaning:

    The failure to develop some part or organplay

    Classified under:

    Nouns denoting natural processes

    Hypernyms ("suppression" is a kind of...):

    development; growing; growth; maturation; ontogenesis; ontogeny ((biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level)

    Credits

     Context examples: 

    A cancer gene that plays a role in the suppression of metastasis, a process whereby cancer spreads from one part of the body to another.

    (Metastasis Suppressor Gene, NCI Thesaurus)

    LAG-3 expression on TILs is associated with tumor-mediated immune suppression.

    (Anti-LAG-3 Monoclonal Antibody BMS-986016, NCI Thesaurus)

    This allele, which encodes acidic leucine-rich nuclear phosphoprotein 32 family member D protein, is involved in the tumor suppression of several types of cancer.

    (ANP32D wt Allele, NCI Thesaurus)

    This results in the suppression of recruitment and activation of tumor associated macrophages (TAM) within the tumor microenvironment.

    (Anti-c-fms Monoclonal Antibody AMG 820, NCI Thesaurus)

    STAT5, a protein often upregulated in cancer cells, plays a key role in signal transduction pathways and the suppression of apoptosis.

    (Multikinase Inhibitor SAR103168, NCI Thesaurus)

    This may result in the activation of c-Jun-NH2-kinase (JNK) and ultimately apoptosis via Bcl2 suppression and caspase-3 activation.

    (Ad-REIC/DKK3 Vaccine, NCI Thesaurus)

    This process is involved in suppression of allergies and induction of sleep.

    (Negative Regulation of Histamine Release, NCI Thesaurus)

    They found that a trade-off exists between force production and sound suppression.

    (Owls' Wings Key to Beating Wind Turbine Noise, The Titi Tudorancea Bulletin)

    This allele, which encodes MAX-interacting protein 1, is involved in transcriptional suppression.

    (MXI1 wt Allele, NCI Thesaurus)

    Other possible antineoplastic activities of this agent include suppression of tumor angiogenesis and tumor growth-promoting insulin-like growth factor 1 (IGF-1).

    (Octreotide Pamoate, NCI Thesaurus)


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