| Library / English Dictionary |
SYNERGISTIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Working together; used especially of groups, as subsidiaries of a corporation, cooperating for an enhanced effect
Example:
a synergistic effect
Synonyms:
Classified under:
Similar:
cooperative (done with or working with others for a common purpose or benefit)
Derivation:
synergism (the working together of two things (muscles or drugs for example) to produce an effect greater than the sum of their individual effects)
Sense 2
Meaning:
Used especially of drugs or muscles that work together so the total effect is greater than the sum of the two (or more)
Synonyms:
interactive; synergistic
Classified under:
Antonym:
antagonistic (used especially of drugs or muscles that counteract or neutralize each other's effect)
Derivation:
synergism (the working together of two things (muscles or drugs for example) to produce an effect greater than the sum of their individual effects)
Sense 3
Meaning:
Of or relating to the theological doctrine of synergism
Classified under:
Relational adjectives (pertainyms)
Pertainym:
synergism (the theological doctrine that salvation results from the interaction of human will and divine grace)
Derivation:
synergism (the theological doctrine that salvation results from the interaction of human will and divine grace)
Context examples:
In mice, SAFit2 reduced stress hormone levels, promoted more active stress coping, was synergistic with antidepressants, protected against weight gain, helped normalize glucose levels and reduced pain in three animal models.
(Depression, Obesity, Chronic Pain Could be Treated by Targeting the Same Key Protein, The Titi Tudorancea Bulletin)
This agent may exhibit synergistic antitumor activity in combination with other chemotherapeutic agents.
(Cyclin D Modulator ON 013105, NCI Thesaurus)
Antiangiogenic drug combination TL-118 is administrated as a specific dosing regimen and may result in a synergistic effect and reduce angiogenesis and inhibit tumor cell proliferation.
(Antiangiogenic Drug Combination TL-118, NCI Thesaurus)
This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents.
(Canertinib dihydrochloride, NCI Thesaurus)
Our findings suggest that combined exposures to alcohol and tobacco have a synergistic effect on SIDS risk, given that dual exposure was associated with substantially higher risk than either exposure alone.
(Combined prenatal smoking and drinking greatly increases SIDS risk, National Institutes of Health)
Although the exact mechanism of action remains to be fully elucidated due to the complexity of the multiple phytochemicals, multifunctional/multitargeted anticancer agent OMN54 appears to work in an additive and synergistic manner by acting on a variety of signaling pathways and on multiple targets, such as vascular endothelial growth factor, nuclear factor kappa B, interleukin-1beta, fibroblast growth factor, and epidermal growth factor.
(Multifunctional/Multitargeted Anticancer Agent OMN54, NCI Thesaurus)
