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Systemic EBV-Positive T-Cell Lymphoproliferative Disease of Childhood
An aggressive and life-threatening, EBV-positive T-cell lymphoproliferative disorder affecting children. It is more prevalent in Taiwan and Japan. Clinically, it presents with acute onset of fever and generalized malaise, followed by hepatosplenomegaly and liver failure. Morphologically it is characterized by the presence of infiltrating T-lymphocytes which are usually small and erythrophagocytosis. Most patients have a fulminant clinical course. (NCI Thesaurus)
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Published by the College of American Pathologists, the Systematized Nomenclature of Medicine Clinical Terms is a combination of content of SNOMED Reference…
