Health / Medical Topics

    T4N5 liposomal lotion

    Pronunciation

    Definition 1

    A lotion being studied in the treatment of skin cancer and a skin condition called xeroderma pigmentosum. It has an enzyme contained in very tiny, fat-like particles. The enzyme repairs damage caused by ultraviolet radiation. T4N5 liposomal lotion is a type of DNA repair enzyme topical agent. Also called Dimericine. (NCI Dictionary)

    Definition 2

    A topical lotion that contains the enzyme T4-bacteriophage endonuclease V encapsulated within liposomes. With topical liposomal delivery, the DNA repair enzyme T4-bacteriophage endonuclease V is transported into skin cells, where the enzyme enters cell nuclei and binds to and incises pyrimidine dimers, thereby catalyzing the first reaction step of the cellular excision repair pathway for removing DNA replication-inhibiting pyrimidine dimers produced within duplex DNA through exposure to ultraviolet (UV) irradiation. In vitro and in vivo studies indicate that T4N5 liposomes increases repair of DNA damage caused by UV irradiation. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of…
    A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of…
    A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of…
    A general term that refers to a TNM finding of a primary tumor with direct invasion of adjacent structures. The definition of…
    The fourth thoracic vertebra counting from the top down.
    A clinical and/or pathologic primary tumor TNM finding indicating direct invasion of adjacent structures by cancer.

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact