| Health / Medical Topics |
T4N5 liposomal lotion
Pronunciation
Definition 1
A lotion being studied in the treatment of skin cancer and a skin condition called xeroderma pigmentosum. It has an enzyme contained in very tiny, fat-like particles. The enzyme repairs damage caused by ultraviolet radiation. T4N5 liposomal lotion is a type of DNA repair enzyme topical agent. Also called Dimericine. (NCI Dictionary)
Definition 2
A topical lotion that contains the enzyme T4-bacteriophage endonuclease V encapsulated within liposomes. With topical liposomal delivery, the DNA repair enzyme T4-bacteriophage endonuclease V is transported into skin cells, where the enzyme enters cell nuclei and binds to and incises pyrimidine dimers, thereby catalyzing the first reaction step of the cellular excision repair pathway for removing DNA replication-inhibiting pyrimidine dimers produced within duplex DNA through exposure to ultraviolet (UV) irradiation. In vitro and in vivo studies indicate that T4N5 liposomes increases repair of DNA damage caused by UV irradiation. (NCI Thesaurus)
YOU MAY ALSO LIKE
