Health / Medical Topics

    T-cell Receptor Excision Circle

    The reciprocal product of T-cell receptor (TCR) gene rearrangement. Following TCR gene rearrangement the T-cell receptor excision circle (TREC) is maintained in the cell as a non-replicating episome. With each cell division the TREC is segregated to a single daughter cell and becomes diluted in the population. Recent TCR rearrangement can be detected by a spike in the number of TREC and can be used to quantify thymic T-cell output. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    This region represents the germline organization of the T cell receptordelta locus. The delta locus includes V (variable), J (joining), diversity (D),…
    One component of the gamma-delta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active…
    This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity…
    One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 7. Somatic recombination results in formation of the active…
    This region represents the germline organization of the T cell receptor alpha locus. The alpha locus includes V (variable), J (joining), and…
    One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact