| Health / Medical Topics |
Tachykinin Receptor 1
Encoded by human TACR1 Gene (GPCR1 Family), 407-aa 46-kDa Tachykinin Receptor 1 is a receptor for the tachykinin neuropeptide substance P and an integral membrane protein with 7 hydrophobic transmembrane regions that probably associates with G proteins that activate a phosphatidylinositol-calcium second messenger system. TACR1 is also involved in mediation of phosphatidylinositol metabolism of substance P. Receptor affinity for tachykinins is: substance P, substance K, neuromedin K. (NCI Thesaurus)
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