| Health / Medical Topics |
Tanomastat
Definition 1
A biphenyl matrix metalloproteinase (MMP) inhibitor (MMPI) with potential antineoplastic activity. Tanomastat inhibits MMP-2, MMP-3, and MMP-9, inhibiting extracellular matrix degradation and potentially inhibiting angiogenesis, tumor growth and invasion, and metastasis. MMPs consist of at least 18 zinc-containing endo-proteinases that are capable of degrading collagen and proteoglycan. (NCI Thesaurus)
Definition 2
An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. (NCI Dictionary)
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