| Health / Medical Topics |
Tasisulam
An acyl-sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used to treat certain types of chronic myelogenous leukemia (CML). It is used in some newly diagnosed patients. It is…
A third generation, synthetic, water-soluble, pentapeptide analog of the marine depsipeptide dolastatin 15, with potential antimitotic and antineoplastic activities. Tasidotin and its…
A synthetic, antiestrogenic steroidal compound with potential antitumor activity. TAS-108 binds to and inhibits estrogenic receptor alpha (ERa), mainly expressed in the…
A quinoline derivative that inhibits both topoisomerase I and II, causing a cytotoxic effect in cancer cells.
A substance being studied in the treatment of several types of cancer and infections caused by certain viruses. It binds to substances…
Tartrate-resistant acid phosphatase type 5b (325 aa, ~37 kDa) is encoded by the human ACP5 gene. This protein is involved in acid…
