Health / Medical Topics |
TBX21 wt Allele
Human TBX21 wild-type allele is located in the vicinity of 17q21.32 and is approximately 13 kb in length. This allele, which encodes T-box transcription factor TBX21 protein, plays a role in the transcriptional regulation of interferon-gamma. Genetic variation is associated with susceptibility to asthma with nasal polyps and aspirin intolerance. (NCI Thesaurus)
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