Health / Medical Topics

    TCF3/HLF Fusion Gene

    A fusion gene (~4.4 kb) that results from a chromosomal translocation t(17;19)(q22;p13) which fuses intron 13 of the TCF3 gene with intron 3 of the HLF gene. This rearrangement is associated with childhood pre-B cell acute lymphoblastic leukemia. (NCI Thesaurus)




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    Human TCF21 wild-type allele is located within 6pter-qter and is approximately 6 kb in length. This allele, which encodes transcription factor 21…
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