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TCF3/PBX1 Fusion Gene
A fusion gene that results from a chromosomal translocation t(1;19)(q23;p13) which fuses intron 13 of the TCF3 gene with exon 2 of the PBX1 gene. This rearrangement is associated with pre-B cell acute lymphoblastic leukemia. (NCI Thesaurus)
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A fusion protein (574 aa, ~59 kDa) encoded by the TCF3/HLF fusion gene. This protein is comprised of the N-terminal transactivation domains…
A fusion gene (~4.4 kb) that results from a chromosomal translocation t(17;19)(q22;p13) which fuses intron 13 of the TCF3 gene with intron…
Expression of a fusion protein that results from a t(1;19)(q23;p13) translocation, which involves the human genes E2A and PBX1 and is associated…
Human TCF3 wild-type allele is located in the vicinity of 19p13.3 and is approximately 43 kb in length. This allele, which encodes…
This gene plays a role in regulation of transcription. It is involved in the control of tissue-specific cell fate during embryogenesis. …
TCF3 fusion partner (253 aa, ~28 kDa) is encoded by the human TFPT gene. This protein plays a role in the promotion…
