Health / Medical Topics

    TCF3-PBX1 Fusion Protein Expression

    Expression of a fusion protein that results from a t(1;19)(q23;p13) translocation, which involves the human genes E2A and PBX1 and is associated with B lymphoblastic leukemias. (NCI Thesaurus)




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    TCF3 fusion partner (253 aa, ~28 kDa) is encoded by the human TFPT gene. This protein plays a role in the promotion…
    Human TCF21 wild-type allele is located within 6pter-qter and is approximately 6 kb in length. This allele, which encodes transcription factor 21…
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