Health / Medical Topics |
TCF3-PBX1 Fusion Protein Expression
Expression of a fusion protein that results from a t(1;19)(q23;p13) translocation, which involves the human genes E2A and PBX1 and is associated with B lymphoblastic leukemias. (NCI Thesaurus)
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Human TCF3 wild-type allele is located in the vicinity of 19p13.3 and is approximately 43 kb in length. This allele, which encodes…
This gene plays a role in regulation of transcription. It is involved in the control of tissue-specific cell fate during embryogenesis. …
TCF3 fusion partner (253 aa, ~28 kDa) is encoded by the human TFPT gene. This protein plays a role in the promotion…
Human TCF21 wild-type allele is located within 6pter-qter and is approximately 6 kb in length. This allele, which encodes transcription factor 21…
This gene plays a role in embryonic trancriptional regulation.
A fusion protein encoded by the TCF12/NR4A3 fusion gene. This protein is comprised of the N-terminus of the transcription factor 12 protein…