Health / Medical Topics

    TCL1B wt Allele

    Human TCL1B wild-type allele is located in the vicinity of 14q32.1 and is approximately 30 kb in length. This allele, which encodes T-cell leukemia/lymphoma protein 1B, may be involved in the modulation of embryogenesis, cell survival and cellular proliferation. The wild-type allele is expressed at elevated levels in T cell leukemias. (NCI Thesaurus)




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