| Health / Medical Topics |
Telomerase Peptide Vaccine GV1001
A synthetic peptide vaccine, containing 16 amino acid residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), with potential antineoplastic activity. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation. Vaccination with the telomerase peptide GV1001 may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against telomerase-expressing cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
Any substance that inhibits telomerase, a ribonucleoprotein enzyme complex that adds telomeric sequences to the 3-ends of eukaryotic chromosomes. Telomerase is quiescent…
Telomerase Cajal body protein 1 (548 aa, ~59 kDa) is encoded by the human WRAP53 gene. This protein is involved in the…
An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell…
A scalp hair loss condition characterized by excessive shedding of hair in the resting phase of growth, usually following a fever or…
A benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1…
An element with atomic symbol Te, atomic number 52, and atomic weight 127.6.
