Telomeric Repeat-Binding Factor 2

Telomeric repeat-binding factor 1 (439 aa, ~50 kDa) is encoded by the human TERF1 gene. This protein is involved in both telomere…

Telomere Shortening occurs every time linear eukaryotic chromosomes are replicated due to premature stoppage of the DNA polymerase complex in the highly…

Telomerase reverse transcriptase (1132 aa, ~127 kDa) is encoded by the human TERT gene. This protein plays a role in both the…

Recombination can lead to the net elongation of telomeres. The sequence at the ends of chromosomes is highly repetitive and is identical…

Telomeres, which define the ends of chromosomes, consist of short, tandemly repeated DNA sequences loosely conserved in eukaryotes. Telomerase is a ribonucleoprotein…

Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a…