Health / Medical Topics |
TFAP2B wt Allele
Human TFAP2B wild-type allele is located within 6p21-p12 and is approximately 25 kb in length. This allele, which encodes transcription factor AP-2 beta protein, is involved in gene expression modulation during ectodermal differentiation. Missense mutations of the wild-type allele can lead to autosomal dominant Char syndrome. (NCI Thesaurus)
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