Health / Medical Topics

    TFIID Subunit Gene

    Human transcription initiation factor TFIID is composed of the TATA-binding protein (TBP) and at least 13 TBP-associated factors (TAFs) that collectively or individually are involved in activator-dependent transcription. Initiation of transcription by RNA polymerase II requires the ordered assembly of basal transcription factors including TFIIA, TFIIB, TATA-binding protein (TBP), TFIIE, TFIIF, TFIIG/TFIIJ, and TFIIH/BTF2 into the TFIID complex. Different activators may interact with specific TAFs to allow the assembly of functionally distinct TFIID complexes that can control transcription of different genes. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    TFIID is a DNA-binding protein complex required for RNA polymerase II-mediated transcription of many, if not all, protein-encoding genes in eukaryotic…
    TFIIA-alpha and beta-like factor (478 aa, ~52 kDa) is encoded by the human GTF2A1L gene. This protein may be involved in the…
    The three subunits of the TFIIA complex (alpha, bet, and gamma) are encoded by the GTF2A1 and GTF2A2 genes. TFIIA has multiple…
    A fusion protein (591 aa, ~66 kDa) encoded by the TFG/NTRK1 fusion gene. This protein is comprised of the N-terminal half of…
    A fusion gene (~2 kb) that results from a chromosomal translocation t(1;3)(q21;q11) that fuses the 5' half of the TFG gene to…
    A fusion protein encoded by the TFG/NR4A3 fusion gene. This protein is comprised of almost the entire protein TFG fused to the…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact