Health / Medical Topics

    TGFBR1 wt Allele

    Human TGFBR1 wild-type allele is located within 9q22 and is approximately 45 kb in length. This allele, which encodes TGF-beta receptor type-1 protein, is involved in TGF-beta signal transduction. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome. (NCI Thesaurus)




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