TGFBR2 wt Allele

Human TGFBR2 wild-type allele is located within 3p22 and is approximately 88 kb in length. This allele, which encodes TGF-beta receptor type-2 protein, plays a role in transcriptional regulation and cellular proliferation control. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. (NCI Thesaurus)

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TGFBR2 Gene

This gene plays a role in cellular proliferation and mitogenic responses.

TGFBR1 wt Allele

Human TGFBR1 wild-type allele is located within 9q22 and is approximately 45 kb in length. This allele, which encodes TGF-beta receptor type-1…

TGFBR1 Gene

This gene is involved in transcriptional regulation and cell cycle progression regulation.

TGFBI wt Allele

Human TGFBI wild-type allele is located in the vicinity of 5q31 and is approximately 35 kb in length. This allele, which encodes…

TGFBI Gene

This gene may play a role in cellular adhesion; however, this function has not been substantiated.

TGFbDNRII-transduced Autologous Tumor Infiltrating Lymphocytes

A preparation of tumor infiltrating lymphocytes (TILs) that are transduced with a retroviral vector encoding a gene for a dominant-negative form of…