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THC
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Psychoactive substance present in marijuana
Synonyms:
tetrahydrocannabinol; THC
Classified under:
Nouns denoting man-made objects
Hypernyms ("THC" is a kind of...):
consciousness-altering drug; mind-altering drug; psychoactive drug; psychoactive substance (a drug that can produce mood changes and distorted perceptions)
Context examples:
This agent exhibits a lower psychotropic potency than delta-9-tetrahydrocannabinol (delta-9-THC), the primary form of THC found in cannabis.
(Delta-8-Tetrahydrocannabinol, NCI Thesaurus)
New preclinical research reported in animal models shows that exposure to compounds found in marijuana called cannabinoids (CBs), which includes cannabidiol (CBD) and tetrahydrocannabinol (THC), during early pregnancy can cause malformations in the developing embryo.
(Using both marijuana and alcohol during early pregnancy may increase the likelihood of disrupting fetal development, National Institutes of Health)
Delta-8-tetrahydrocannabinol (delta-8-THC) binds to the cannabinoid G-protein coupled receptor CB1, located in the central nervous system; CB1 receptor activation inhibits adenyl cyclase, increases mitogen-activated protein kinase activities, modulates several potassium channel conductances and inhibits N- and P/Q-type Ca2+ channels.
(Delta-8-Tetrahydrocannabinol, NCI Thesaurus)
