Three Prime Repair Exonuclease 2

Encoded as alternative isoforms by TREX2 Gene, Three Prime Repair Exonuclease 2 contains 3 conserved exonuclease motifs and catalyzes nucleoside monophosphate excision from 3-prime DNA termini and may be a subunit of DNA polymerase III. 26S Proteasome-Associated UCH Interacting Protein 1 results from use of a different open reading frame of TREX2 Gene, producing a protein structurally unrelated to the other isoforms that interacts with Ubiquitin C-Terminal Hydrolase 37, which may edit polyubiquitin chains on ubiquitinated substrates. Ubiquitin C-Terminal Hydrolases (UCH) hydrolyze C-terminal esters and amides of ubiquitin to generate free monomeric ubiquitin from ubiquitin proproteins, but do not deubiquitinate ubiquitin-protein conjugates or disassemble polyubiquitin chains. (NCI Thesaurus)

YOU MAY ALSO LIKE

Three Prime Repair Exonuclease 1

Three prime repair exonuclease 1 (369 aa, ~39 kDa) is encoded by the human TREX1 gene. This protein is involved in DNA…

Three Pack

A product containing three individual units.

Three Dimensional Imaging

Technique to produce 3D images to provide the ability to visualize important structures in great detail. Traditionally CT and MRI scans produced…

Three

A natural number greater than 2 and less than 4 and the quantity that it denotes: the sum of two and…

Threatened Premature Labor

Frequent painful contractions prior to 37 weeks of gestation without cervical change.

Threatened Abortion

Vaginal bleeding preceding the 20th week of gestation.