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THYMINE
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I. (noun)
Sense 1
Meaning:
A base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine
Synonyms:
Classified under:
Hypernyms ("thymine" is a kind of...):
pyrimidine (any of several basic compounds derived from pyrimidine)
Holonyms ("thymine" is a substance of...):
deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)
Context examples:
There are four nucleotides, or bases, in DNA: adenine (A), cytosine (C), guanine (G), and thymine (T).
(Base pair, NCI Dictionary)
DNA Synthesis is the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.
(DNA Synthesis, NCI Thesaurus)
This allele, which encodes dihydropyrimidine dehydrogenase [NADP+] protein, plays a role in the reduction of uracil, thymine and the drug 5-fluorouracil.
(DPYD wt Allele, NCI Thesaurus)
A molecule consisting of a nitrogen-containing base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate group, and a sugar (deoxyribose in DNA; ribose in RNA).
(Nucleotide, NCI Dictionary)
DNA Synthesis Induction consists of the initiation of activities involved in the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.
(DNA Synthesis Induction, NCI Thesaurus)
DNA Synthesis Inhibition involves interference with, or restraint of, the activities involved in the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.
(DNA Synthesis Inhibition, NCI Thesaurus)
Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis.
(Nolatrexed Dihydrochloride, NCI Thesaurus)
A radioconjugate comprised of the synthetic pyrimidine analogue 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)thymine (d-FMAU) labeled with the radioisotope fluorine F 18 (18F-d-FMAU), that can potentially be used as an imaging agent upon positron emission tomography (PET).
(Fluorine F 18 d-FMAU, NCI Thesaurus)
A subunit of DNA or RNA consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA and ribose in RNA).
(Nucleotide, NCI Thesaurus)
Two nitrogen-containing bases pair together between double-stranded DNA; only specific combinations of these bases (e.g., adenine with thymine; guanine with cytosine) are possible, a fact which facilitates accurate DNA replication; when quantified (e.g., 8 base pairs, or bp), this term refers to the actual number of base pairs in a sequence of nucleotides.
(Base pair, NCI Dictionary)
