Tiomolibdate Diammonium

Definition 1

An ammonium salt with potential antiangiogenic and antitumor activities. Tetrathiomolybdate has been found to deplete systemic copper reserves through an unknown mechanism. This agent has been shown to inhibit the activities of cuproenzymes, including superoxide dismutase 1 (SOD1) and cytochrome c oxidase (COX), which may contribute to its antiangiogenic and antitumor effects. (NCI Thesaurus)

Definition 2

A substance being studied in the treatment of many types of cancer. Ammonium tetrathiomolybdate removes extra copper from the body. Removing the copper may prevent the growth of new blood vessels that tumors need to grow and may kill cancer cells. Ammonium tetrathiomolybdate is a type of chelating agent and a type of antiangiogenesis agent. (NCI Dictionary)

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