Health / Medical Topics

    Tipifarnib

    Pronunciation

    Definition 1

    A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. Also called R115777 and Zarnestra. (NCI Dictionary)

    Definition 2

    A nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A regimen consisting of paclitaxel, ifosfamide, mesna and cisplatin used for the treatment of advanced-stage testicular cancer; also used for the treatment…
    The extreme end of something, especially something pointed.
    A coil associated with a tip conductor voltage tester.
    The pointed end of a linear structure.
    The monohydrate bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a long-acting muscarinic receptor antagonist, with bronchodilating…
    The bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity. Although it…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact