| Health / Medical Topics |
Tissue Inhibitor of Metalloproteinases
Definition 1
Tissue inhibitors of metalloproteinase. A family of proteins of around 200 residues that can inhibit enzymes of the metalloprotease type, for example collagenase, by binding to them. (DCB-CB) (NCI Thesaurus)
Definition 2
21-27 kDa proteins found in the extracellular matrix; regulate the activity of collagenase and therefore are important in tumorigenesis, angiogenesis, chondrosteosis, and other tissue forming processes. (NIH CRISP Thesaurus)
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