TK2 wt Allele

Human TK2 wild-type allele is located within 16q22-q23.1 and is approximately 40 kb in length. This allele, which encodes thymidine kinase 2, mitochondrial protein, is involved in the mitochondrial salvage pathway and plays a role in the phosphorylation of thymidine, deoxycytidine, and deoxyuridine. Certain allelic variants of the TK2 gene are associated with myopathic mitochondrial DNA depletion syndrome. (NCI Thesaurus)

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TK2 Gene

This gene plays a role in mitochondrial DNA synthesis in non-replicating cells.

TK1 wt Allele

Human TK1 wild-type allele is located within 17q23.2-q25.3 and is approximately 13 kb in length. This allele, which encodes thymidine kinase, cytosolic…

TK1 Gene

This gene is involved in the metabolism of nucleosides, nucleotides and nucleic acids in the cytosol.

TK Gene

The TK Gene encodes thymidine kinase, a transferase class pyrimidine salvage enzyme that catalyzes ATP-dependent phosphorylation of thymine deoxyribonucleoside. The TK gene…

Tizolemide

An alkaline sulfonamide-based diuretic. Tizolemide inhibits sodium reabsorption in the distal convoluted tubules.

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The hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant property. Tizanidine…