TLR4 wt Allele

Human TLR4 wild-type allele is located within 9q32-q33 and is approximately 11 kb in length. This allele, which encodes toll-like receptor 4 protein, is involved in pathogen recognition, signal transduction and innate immunity. Mutations in the gene are associated with differences in LPS responsiveness. (NCI Thesaurus)

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TLR4 Gene

This gene is involved in the mediation of immune responses and in signal transduction events induced by lipopolysaccharide.

TLR3 wt Allele

Human TLR3 wild-type allele is located within 4q35 and is approximately 16 kb in length. This allele, which encodes toll-like receptor 3…

TLR3 Gene

This gene is involved in innate antiviral responses.

TLR2 wt Allele

Human TLR2 wild-type allele is located within 4q32 and is approximately 18 kb in length. This allele, which encodes toll-like receptor 2…

TLR2 Gene

This gene plays a role in pathogen recognition and mediates the host response to gram-positive bacteria and yeast.

TLR1 wt Allele

Human TLR1 wild-type allele is located within 4p14 and is approximately 9 kb in length. This allele, which encodes toll-like receptor 1…